In the last decade the femicide has become one of the most frequent types of killings in the world, especially in Latin American countries. Despite the great strides to achieve gender equity, violence against women persists in society. The objective of this paper was to perform a tweets analysis of feelings and opinions from the social network Twitter related to the femicide in Colombia and Mexico, which has become a widely debated topic in the world. 300 tweets of Colombians and 300 tweets of Mexicans were collected. The opinions of Mexicans were considered to analyze the public perception that other people have different to Colombians. A comparative analysis was developed; the results of the Colombians were different from Mexicans. The tweets of Mexicans have more negative feelings compared to the Colombians tweets. In comparison with the proportion of tweets with negative feelings of Mexicans, 83%, the percentage of Colombians tweets is 74%.